Shikimic acid introduction
Shikimic acid is a white crystalline compound of nonnitrogenous acid found in various plants naturally. It has two kind functional groups in the same molecule, three hydroxyl groups and a carboxylic acid group, which are optically active.
They can yield various kinds of esters and salts. Shikimic acid is a cyclitol, a polyhydroxylated cycloalkane containing at least three hydroxy groups in the ring at different positions. Examples are inositol and quinic acid.
The most important feature of cyclitol is that there are chiral isomers, key intermediates in the biosynthesis of aromatic compounds in living metabolism. Shikimic acid is a key intermediate in the biochemical pathway from phosphoenolpyruvic acid to tyrosine.
Details of parameters
|Product Name:||Shikimic acid|
|Synonyms:||Kava root extract;L-SHIKIMIC ACID|
|Product Categories:||Natural Plant Extract;API|
Melting point of 185-187 ° C (lit.)
Specific rotation -180 ° (C =4,H2O25 ° C)
The boiling point of 225.11 ° C (roughestimate)
1.52 g/cm3 density (27.2 ℃)
The refractive index - 180 ° (C = 1, H2O)
Storage condition: -20°CFreezer
Solubility of 180 g/l
Acidity coefficient (PKA) PK (14.1°)5.19
Optical rotation (opticalactivity) [alpha] / ChemicalbookD - 180.0 + / - 5.0 °, c = 4 inh2o
Water solubility 18g/100mL(20 ° C)
Sensitivity HygroscopicMerck14, 8480 brn4782717inchikeyjxohggnkmltubp - HSUXUTPPSA - NCAS
Database 138-59-0 (CASDataBaseReference)
(IARC) Classification of Carcinogens 3(Vol.40,Sup7)1987NIST
Information on Chemical Substances
1.Shikimic acid effected by arachidonic acid;
2.Shikimic acid acts as anti-inflammatory ,analgesic;
3.Shikimic acid is the drug intermediates of anti-cancer and anti-virus;
4.Moreover, shikimic acid is also the basis raw materials of combating avian flu;
5.Shikimic acid can inhibit the concentrating of the blood platelets,inhibit arterial,venous thrombosis and cerebral thrombosis;
6. It also as antiviral and anticancer medicine intermediates.